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Advanced course: Disciplinary training - Computational Genomics and Epigenomics - how to interpret expression data May 12, 26, June 9, 16

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Advanced course: Disciplinary training - Computational Genomics and Epigenomics - how to interpret expression data

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Academic year 2020/2021

Teacher
Paolo Provero (Lecturer)
Year
1° anno, 2° anno
Teaching period
Secondo semestre
Type
indirizzo Neuroscienze Sperimentali
Language
Inglese
Prerequisites
Prerequisites:
- elementary statistics (descriptive statistics, estimation, hypothesis testing, linear regression)
- R language at elementary level (to be discussed with the teacher Prof Paolo Provero)
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Sommario del corso

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Course objectives

The course aims to introduce the students to omic data, with particular focus on transcriptomics and ChIP-seq data, and to the principles of their statistical analysis and biologicla interpretation

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Results of learning outcomes

- understanding omic data and the main techniques fo their analysis

- understanding how to extract biological information from omic data

- ability to perform simple analyses of transcriptomic data (class comparison, class discovery, enrichment analysis)

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Program

- Introduction to omics

- Analysis of gene expression data: class comparison

- Analysis of gene expression data: class discovery

- Functional enrichment analysis

- Analysis of ChIP-seq data

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Course delivery

Lectures and practical sessions in computer room

Lectures scheduled on:

May 12, 26, 3-5pm

June 9, 16, 3-5pm

Practical activities will be planned in September

Suggested readings and bibliography



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