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Advanced course: Glycogen synthase kinase-3 (GSK-3): role in mood disorders _ May 20, 2021
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Advanced course: Glycogen synthase kinase-3 (GSK-3): role in mood disorders-May 20, 2021
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Academic year 2020/2021
- Teachers
- Giuseppe Maina (Lecturer)
Filippo Tempia (Lecturer)
Eriola Hoxha (Lecturer)
Gianluca Rosso (Lecturer) - Year
- 1° anno, 2° anno, 3° anno, 4° anno
- Teaching period
- Secondo semestre
- Type
- indirizzo Neuroscienze Sperimentali
- Course disciplinary sector (SSD)
- BIO/09 - physiology
MED/25 - psychiatry - Delivery
- A distanza
- Language
- Inglese
- Attendance
- Facoltativa
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Sommario del corso
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Course objectives
Mood disorders are a group of chronic and disabling mental illnesses with a complex pathophysiological basis. The identification of potential biomarkers is fundamental to improve the management and treatment of patients with mood disorders. Glucogen synthase kinase-3 (GSK-3) is a multifunctional enzyme with a crucial role in the etiology and treatment of mood disorders. Recent findings suggested GSK-3 as a putative biomarker in mood disorders, both for differential diagnosis between Major Depressive Disorder (MDD) and Bipolar Disorder (BD), and to reflect disease state and/or treatment responses.
Specific objectives and learning outcomes:
- to provide an overview of mood disorders;
- to provide an overview of the role of biomarkers in the diagnosis of mood disorders;
- to deepen the putative role of biomarkers in the treatment of mood disorders;
- to know the transduction pathways in which GSK-3 in involved;
- to discuss the putative role of GSK-3 as a novel biomarker or as a therapeutic target;
- to understand the current knowledge about the neural mechanisms of mood disorders;
- to understand the role of GSK-3 in the control of neuronal activity.
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Program
May 20th, 2021 (9am - 1pm)
9-10: Introduction and overview (Giuseppe Maina)
10-11: Biomarkers and mood disorders (Gianluca Rosso)
11-12: GSK-3 signaling (Filippo Tempia)
12-13 GSK-3 alterations in mood disorder (Eriola Hoxha)
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Course delivery
via webex
link: https://unito.webex.com/meet/giuseppe.maina
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Learning assessment methods
At the end of the Course, a short multiple-choice questionnaire will be presented to the students to verify the level of learning achieved.
Suggested readings and bibliography
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Notes
Coordinators: Giuseppe Maina (giuseppe.maina@unito.it), Filippo Tempia (filippo.tempia@unito.it)
Teachers: Giuseppe Maina, Filippo Tempia, Gianluca Rosso, Eriola Hoxha
- Enroll
- Open
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