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Emma Merlin

Contacts

Supervisor

Francesco Ferrini
Adalberto Merighi

Curriculum vitae

Curriculum Vitae

Phd thesis

Pain is perceived by the integration and processing of sensory stimuli conveyed to the different areas of the central nervous system through nociceptive pathways. My Ph.D. project aims to analyze the involvement and activation of inhibitory neurons in the spinal dorsal horn and somatosensory cortex using a model of inflammatory pain induced by zymosan injection in the hind paw of both normal and diabetic mice. To conduct this analysis, immunohistochemical approaches, and functional studies will be carried out to evaluate activation in inhibitory neurons and to identify the specific circuits involved. Behavioral tests will also be associated to assess the level of noxious sensitivity. The results obtained will improve the knowledge of the role of inhibitory neurons leading to a better understanding of how the perception of pain is regulated and modulated at the spinal and supraspinal levels, which is fundamental for the development of more effective treatments.

Research activities



2024

"Advances in diagnosis and treatment of mood disorders: studies on biomarkers and drug repurposing" - G.Rosso, G.Di Salvo - May 10th - 1,5 ECTS

"Basic of Project WritingC.Abrescia - May 6th 0,5 ECTS

"Corso di formazione SPECIFICA alla Salute e Sicurezza per i Lavoratori (artt. 37-169-227-239-278 del DLgs 81/08) - Rischio Alto - Settore Ateco 2007 Q 86" - e-learning - April 4th - 4,5 ECTS

"From neural cell excitability to brain circuit recording, visualization and manipulation” - E.Hoxha, F.Ferrini, V.Carabelli, S.Bovetti, S.Zucca, G.Concina - February 14th, 23rd, 28th; March 6th, 13th, 20th - 4,5 ECTS

"First Year PhD Data Report - XXXVIII cycle" - presenting- February 15th0,5 ECTS

2023

"Welcome meeting XXXIX cycle and 2nd Enrica Marzola award ceremony" - November 30th

"Research Professional Platform: fund your research!” - I.Riondato - October 18th - 1 ECTS

"Last year data reports by the PhD Students of the 35th cycle" - attendance - October 16th - 0,5 ECTS

"Neuromuscular disorders in the era of advanced therapies: new perspectives for clinical and transitional research" T.E.Mongini - September 20th, 22th - 3 ECTS

"Soft Skills: PREPARARSI ALLA SELEZIONE: DAL CV AL COLLOQUIO DI LAVORO" - M.Molino - September 13th - 0,25 ECTS

"Soft Skills: LAVORARE IN GRUPPO NELLE ORGANIZZAZIONI" - C.Cortese - September 13th - 0,25 ECTS

"Neuropsychophysiology of the placebo and nocebo phenomena" - M.Amanzio - June 9th, 16th, 23th - 1,5 ECTS

"Basic of Project WritingC.Inaudi - May 3th - 0,5 ECTS

"FAIR Data" E.Giglia - April 27th, 28th - 1,37 ECTS

"Knowledge Transfer" - O.Bertoia - April 20th - 0,37 ECTS

"Open Science A to Z" E.Giglia - April 17th, 18th - 1,75 ECTS

"Ethics of research and Responsible research: an introduction" - D.Ovadia - March 13th, 14th - 2 ECTS

"First Year PhD Data Report - XXXVII cycle" - attendance - 15th February - 0,5 ECTS

"Introduction to research methodology" - D.Romano - February 10th, 17th - 3 ECTS

"Workshop on bibliographic research" - L.Garbolino, B.Martin - January 17th, 25th; February 1st - 2,25 ECTS

"Clinical, methodological and theoretical aspects of translational and cognitive neuroscience" - A.Berti, A.Chiò, M.Giustetto - January 11th - 2 ECTS

2022

"Welcome meeting XXXVIII cycle and 1st Enrica Marzola award ceremony" - December 7th

"Workshop: Public engagement and outreach" - A.Buffo + invited speakersNovember 18th, 19th - 2,5 ECTS

"Corso di formazione generale alla salute e sicurezza per i lavoratori" - e-learning - May 5th - 1 ECTS



2024

Workshop

"My 3-minute PhD thesis challenge" - UNITA April 4th, 12th, 19th 

Seminar

"Using fNIRS to investigate the development of functional connectivity and its relationship with social development and early adversity" - C.Bulgarelli - April 16th - 0,5 ECTS

"Cellular Crosstalk in Neurodevelopmental Disorders" S.Cappello - February 21st - 0,5 ECTS

"Creatine Transporter Deficiency: the long journey to successful therapy" - L.Baroncelli - January 24th0,5 ECTS

2023

Workshop

"FI(na)LMENTE - Comunicare la scienza. Pillole di storytelling & filmmaking" - April 21th, 26th; May 5th, 12th, 17th

Journal club

"Mouse models of diabetes: focus on sex differences" - Presenting - March 3rd - 1 ECTS

Seminar

"Information decomposition and the informational architecture of the brain" A. Luppi - October 12th - 0,5 ECTS

"Satellite Glial Cells. Two decades of Progress" M. Hanani - October 6th - 0,5 ECTS

"Optical analysis of neuronal ionic currents in acute brain slices"M. Canepari - June 26th - 0,5 ECTS

"Gender dimension in research" - V. De Luca - June 23th - 0,5 ECTS

"Choroid plexus: a new entry point to study the brain development" - A. Patrizi - May 30th - 0,5 ECTS

"A Space For My Body"D.Romano - February 17th - 0,5 ECTS



2023

Congress

"Recruitment of inhibitory neurons in a murine model of inflammatory pain" E.Merlin, C.Salio, F.Ferrini - 6th Brainstorming research assembly for young neuroscientists (BraYn), Poster - September 27th

"Recruitment of inhibitory neurons in a murine model of inflammatory pain" - E.Merlin, C.Salio, F.Ferrini - 20th Italian Society for Neuroscience (SINS) National Meeting, Oral presentation - September 15th

"Recruitment of inhibitory neurons in a murine model of inflammatory pain" - E.Merlin, C.Salio, F.Ferrini - SINS National Meeting of PhD Students in NeurosciencePoster - September 14th

2022

Congress

"Recruitment of spinal inhibitory neurons in inflammatory pain" - E.Merlin, C.Salio, F.Ferrini - 75th Convegno SisvetOral presentation - June 17th

Public engagement

"Recruitment of spinal inhibitory neurons in inflammatory pain" - E.Merlin, C.Salio, F.Ferrini - 2nd Game of Research - Department of Veterinary Sciences (UniTo)Oral presentation - December 15th

2023

6th Brainstorming research assembly for young neuroscientists (BraYn) - Napoli (Italy) - September 27th-29th

20th Italian Society for Neuroscience (SINS) National Meeting - Torino (Italy) - September 14th-17th

SINS National Meeting of PhD Students in Neuroscience - Torino (Italy) - September 14th

2022

75th Convegno Sisvet - Lodi (Italy) - June 16th,17th

2024

"Inhibitory neurons in pain pathways: recruitment and function in physiological and pathological conditions" 
- May 10th - "My 3-minute PhD thesis challenge" local competiton

2023

"FI(na)LMENTE - Comunicare la scienza. Pillole di storytelling & filmmaking" - 
June 8th - "Qualche millesimo di secondo prima" - G.Esposito, C.Maronati, E.Merlin, C.Parise, R.Vada

2022

"Recruitment of spinal inhibitory neurons in inflammatory pain" - E.Merlin, C.Salio, F.Ferrini - 2nd Game of Research - Department of Veterinary Sciences (UniTo)Oral presentation - December 15th

Last update: 13/05/2024 10:03
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